Hypnos gathers the four gods who control dreams. One of them, the Vision Icelus, appears in Sagittarius, avoiding Capricorn El Cid's attacks, and steals the soul of the unconscious Sisyphus. El Cid leaves the Sanctuary alone to get it back. El Cid, who had always been by Sisyphus side, felt the reason why he wouldn't wake up...

Thanatos finally gets serious after being wounded by Manigoldo. But even in the worst position imaginable, Seiji doesn't falter. Don't use the word despair so loosely, he says, and Manigoldo remembers his old days with his master and regains hope. The two use their Sekishiki Meikaiha attack in a final desperate attempt, and succeed in separating Thanatos soul from his body, but...

Manigoldo finds the location of the Twin Gods, but is helpless before the might of Thanatos, the God of Death. The Pope Seiji arrives to help him. As he struggles to withstands Thanatos’s attacks, Manigold remembers how he met Seiji when he was young. Manigoldo, a war orphan, once thought that human life was valueless… As Thanatos finally reveals his true strength, is there any way for them to win?

Tenma, Yato, and Yuzuriha are surrounded by Veronica’s zombies, only to be saved by Cancer Saint Manigoldo. Manigoldo had come to protect Tenma at the pope’s orders. With his overwhelming power, he splits Veronica’s body in two. But even this isn’t enough to kill him, and Veronica tries to cause them all to rot along with the forest. Meanwhile, the Twin Gods Hypnos and Thanatos watch the battle from the palace as they play Chess…

Upon entering the forest of Death, Yuzuriha is separated from the others. She is confronted by her brother, who she thought died years ago. His voice sends her back to the past… Meanwhile, Yato is cornered by a giant centipede. As his consciousness fades, he too remembers his past. Will the two arrive in time to help Tenma in his desperate battle against the Specter Veronica?

Pandora seals away Alone in his studio so that he can focus on the creation of the “Lost Canvas,” and completely awakens as the King of Hades. In the shadows, Hades’ Councilors Hypnos and Thanatos, worried about the Pegasus Saint and his connections to Hades, begin to take action. At the Pope’s orders, the Cancer Saint Manigoldo follows after Tenma. On his way to Hades Castle, Tenma reaches the spot where his old village was destroyed, but in its place he finds a gigantic and sinister forest.

Tenma leaves the Sanctuary and has resolved to fight on his own. However, on orders from the Pope, he is stopped by the Cancer Golden Saint Manigold and locked in a cell. Back at the Hades palace, so as to fully awaken Hades, who’s full reincarnation is prevented by Alone’s memories, Hypnos and Thanatos encourage Pandora to trap Hades into an atrium.

The painting covering the whole sky, “The Lost Canvas,” is said to destroy everyone on earth when completed. Tenma hears to his dismay that the once kind Alone is now trying to destroy all of humanity as Hades. Meanwhile, Pandora desperately realizes that the reincarnation of Hades is incomplete, and sends an assassin to kill Tenma, who is stopping the completion of the reincarnation. The Specters use ultrasonic waves to put Tenma and the others asleep, however…

Tenma finally returns to the Sanctuary, and challenges Alone to a fight, only to have the tables turned. Then, the Pope arrives and uses an amulet from a previous incarnation of Athena to release the “Talisman Cage” and weaken Hades’ power. He tries to seal Hades in the Sanctuary using Athena’s cosmos. However, Pandora rushes over…

Aldebaran bears Kagaho’s powerful attack, and defeats him with the “Titan’s Nova,” a move so powerful it breaks the earth. However, Aldebaran feels Kagaho is not a threat, and does not finish him off. The hurt Kagaho flies away into the twilight sky. Later at the Sanctuary, Athena’s protective spell is violently torn by a giant cosmos. Lord Hades appears before Sasha!

The Crusades. The battles that take place every 200 or so years between the Goddess Athena and Hades, the Lord of the Underworld. In an 18th century European country town, just as the Crusade is dawning, live Tenma and Alone. They have completely different personalities but are the best of friends. One day, Alone meets a woman named Pandora. From that day, the cogs of fate are set into motion.

Miyano struggles to figure out what to tell Sasaki. Sasaki gets sick. The day of the cultural festival finally arrives.

Ogasawara gets Miyano's help with another lovers' quarrel. Preparations for the cultural festival begin in earnest. As the Chairman helps Miyano with his look for the cross-dressing competition, Miyano seeks his wisdom about love.

Miyano finds out the cultral festival will have a cross-dressing competition. As Sasaki does his best to wait patiently for Miyano's answer about his feelings, a familiar face from Miyano's past brings Miyano new perspective.

Despite pouring over the issue, Miyano struggles to define how he feels about Sasaki. In a rare moment alone with Sasaki, Miyano works up the courage to address his feelings.

Sasaki finally decides to tell Miyano how he feels. However, Sasaki's nerves get to him and make him say the wrong thing. Can he find a way to fix his mistake?

Sasaki becomes less and less able to hide his feelings. Ogasawara gets fujoshi help from a fudanshi. Miyano continues to question his relationship with Sasaki.

As Miyano continues lending Sasaki BL manga, he worries he might be bringing Sasaki negative attention. Miyano begins to question the nature of Sasaki's relationship with him.

The school year slowly marches forward. As Sasaki and Miyano's relationship deepens, the other guys at school take notice. Sasaki struggles with the intensity of his feelings.

With the school field trip over and entrance exams approaching, the seniors are passing on their positions. As the Discipline Committee finishes its transition meeting, a student reports a special item missing. Can they solve the mystery?