Life's great in this world, except for one thing: there's no alcohol! When the students sneak into the principal's office to get their fix from his stash, they run into more than they bargained for.

Having made tremendous advances, breaking through everything in their path since their Hunter debut, the Crimson Vow is now being treated as the next generation of ace Hunters by the Guild. They take on a difficult quest that other Hunters shy away from, but, lurking in the shadows of the quest, beastpeople are on the move. And it seems even that is not all there is to this quest... The Crimson Vow faces its most dire threat ever. The greatest of enemies appears before Mile!

Dale and Latina begin their return to Kreuz, and along the way, pick up some souvenirs for their friends back home.

Inojin approaches his parents about mastering the Mind Transfer Jutsu. Cho-Cho agrees to assist and everything is set for training to begin. With his father Sai observing, Inojin starts training with Ino. But due to his lack of confidence, Inojin's unable to execute the jutsu, which ends up irritating his mother

Dogstorm fights against Shutenmaru to ally with him for their operation but Shutenmaru still rejects their call. Meanwhile, Sanji and the others are on their mission to recruit like-minded people who become skeptical as they receive the secret message from the Kozuki Clan.

The Misfit Class is in the middle of a flying race in order to determine their ranks. Since Iruma is human, he can’t fly, so he’s riding on the back of the giant baby demon bird, but it seems to be flying off course. Meanwhile, Sabnock decides to go through the treacherous Cutthroat Valley and ends up having to battle it out with the Guardian there. Sabnock is obsessed with becoming the next Demon King, but why is he so obsessed? Are Iruma and Sabnock going to be able to make it out of Cutthroat Valley alive?

Iroha remembers that her wish was to cure her younger sister, Ui’s, illness; however, there is no sign of Ui’s existence in her life. She goes to Kamihama City to find clues about her, but is attacked by a Witch and subsequently saved by a trio of Magical Girls, Momoko, Rena, and Kaede. There is a rumor going around about the Friendship Ending Staircase at Rena and Kaede’s school. Momoko and the others believe that a Witch is involved in the rumor, so they’ve been investigating it, but…

The truth is finally out, and it's not only our heroes who take notice. With everything at stake, it's all hands on deck to protect the City of Mantle.