The one who greets Shinemon and friends from mysterious research laboratory "Ryuzu's Lab" is none other than Tatsuya. Shinemon challenges the head of the lab Ryuzu Myoujin to a fight, and bears witness to a shocking experiment.

As the heroes deal with the aftermath of the fight with the Shie Hassaikai, the vehicle transporting Chisaki has an encounter with the League of Villains...

As the Daihasei Festival begins, Uiharu and Saten enjoy themselves, while Kuroko sees to her Judgment duties. Mikoto and Kongo run an eventful three-legged race against teams from other schools. A plot involving MEMBER begins going into motion.

Ringo focuses on developing the item Tsukasa requested while he endures the weight of that request. Shinobu continues to gather information, but shows concern for Jeanne when she uncovers the Azure Brigade's suspicious activity. Meanwhile, a plague strikes the city. Its treatment is beyond the doctors of this other world, and with the group's reserves of medical supplies running low, the patients are facing the risk of death. When the local Medical Guild comes to insult the Seven-Light Faith for failing to save their patients, Akatsuki gets mad. That's when the world's greatest doctor, Kanzaki Keine responds to his spirit and declares that she will make medicine to save them all.

With the paper-making process about to begin, Main can't hide her excitement as she and Lutz go to meet Benno as per his invitation. He reveals that he is willing to arrange for all the equipment and materials they need to make the paper, but the ensuing conversation makes Lutz see Main in a very different light.