Having won the Grand Bout fair and square, and having cured village priestess Ruri of her pneumonia, Senku has won the hearts and minds of the village. Ruri delivers Senku a message from someone dear.

With Magma defeated, it’s down to Senku and Ginro to take the throne. Although both are on the same team, one is driven by personal greed and opportunism. The fight is on!

The Grand Bout is on. The kingdom of science must defeat Magma and take the seat of the village chief in order to give Ruri the antibiotic and win over the village.

All that’s needed to make antibiotics is alcohol. The best way to get some is to win the Grand Bout, which the Senku and his kingdom will also need to do in order to keep Magma away from Ruri and give her the drug.

To make antibiotics, Senku and his kingdom need to obtain sulfuric acid from a fountain of the stuff. The team goes prepared, but there’s no guarantee that they’ll make it back alive.

The development of glassworks, an important step for making sulfa drugs and for chemistry as a whole, turns out to have a surprising benefit for Suika.

Senku and his kingdom of science successfully test the first lightbulb since the collapse. Meanwhile, Asagiri Gen, a spy from Tsukasa’s empire, is killed by an unknown attacker.

Senku and Taiju emerge from their petrification several thousand years after everyone in the world had turned to stone. It’s up to them to rescue everyone else and restore civilization.

Trillion Game, Inc. takes over God Promotion's shareholder meeting, and Gaku learns the shocking truth about Haru's plans for Sakura and his team of game designers.

July 1st, 2030. Manga editor Nishino Mizuho is having the worst 27th birthday ever. The manga she’s in charge of will be ending. However, when she sees a group of high school students having fun, she recalls her own adolescence. 10 years ago, during her second year of high school, Mizuho had four childhood friends who she grew up with in a residential neighborhood known as Koigahama Highlands…

Kenshin undergoes training so that he can learn the ultimate technique. He barely manages to get in a hit against Seijuro in a bout, where he then learns "Kuzuryuusen,"a powerful technique that launches nine slashes at the same time. Kenshin learns to see through Seijuro's swift sword movements and masters "Kuzuryuusen" by looking at it only once. However, the technique was only born out of the process of passing down the ultimate technique, "Amakakeru Ryuu no Hirameki" of Hiten Mitsurugi-ryu.

Gaku and Rinrin meet with Hebijima, the creator of Dragon Bank's hit game Dragon Musume, to offer him a job at Trillion Game, Inc. Negotiations immediately hit a snag when the topic of pay comes up.

Afraid of ruining their relationship, Mizuho tells herself not to fall for Kizuki. All the stress makes her ill, and her friends come to help.

A sudden snowstorm forces the girls to take refuge in a school.

The universe's ability to self-correct made Sayo's funeral occur before her death. It seems only the Elements are aware that Sayo was in their class, but when Momohime asks about it, the students share a vision of a super-civilization with winged beings.

Ave Mujica continues to develop thanks to Mutsumi. There is no trace of the previous discord, and all its members are in harmony.

With the artificial spirit eye that Yuri bestowed upon him, and with Ursula's training, Ein has gotten stronger. When he sets his sights on reaching the surface, Yuri asks him to take her with him. To that end, Ursula further enhances both his eyes, and they are ready to leave. That's when Yuri asks Ein a certain question...