Kohaku shows Senku to her village, but it’s going to take some convincing before they let him in. In the meantime, he makes friends with a like-minded, promising “sorcerer.”

Tsukasa has learned about the cave where the nitric acid is collected. The race is on between Senku and Tsukasa to restore humanity in their respective visions.

The morse code signal reading "WHY" saturates the airwaves too much for Ukyo to pinpoint a direction, so the Kingdom of Science works on a way to visualize the signal.

The development of glassworks, an important step for making sulfa drugs and for chemistry as a whole, turns out to have a surprising benefit for Suika.

The Perseus crew are on their way to the treasure island, the birthplace of the Hundred Tales, where they hope to locate the treasure box left behind by the Soyuz crew.

Kaseki's efforts to build the science vessel Perseus hit a roadblock when he realizes that it's impossible to get all the parts to fit in practice.

The Perseus arrives at the treasure island. A recon squad consisting of Senku, Soyuz, Kohaku, and Gen set off to locate the platinum and make contact with the islanders. Ukyo later discovers something on the seafloor and send Ginro to investigate.

Amaryllis explains how she evaded petrification and how she came to her decision to sneak into the inner palace.

Suika and Ginro work together to rescue the mobile lab from the Perseus. Reunited with Senku and the others, the group works on items to help Kohaku with the selection process.

With Magma defeated, it’s down to Senku and Ginro to take the throne. Although both are on the same team, one is driven by personal greed and opportunism. The fight is on!

Senku, brings along a team to look for the Sagara Oil Fields. Meanwhile, Suika and Francois go truffle hunting.

All that’s needed to make antibiotics is alcohol. The best way to get some is to win the Grand Bout, which the Senku and his kingdom will also need to do in order to keep Magma away from Ruri and give her the drug.

The Kingdom of Science will need rations to last them through their voyage to the other side of the world. But Senku, being no professional, burns all the bread he attempts to bake.

Senku starts a ramen stand in hopes of winning over support for his kingdom of science, but some people are too principled to take such a bribe. Mentalist Asagiri Gen is not one of them.

While continuing to use the hot air balloon to search for the oil, it's decided that Ishigami Village needs to take up agriculture to prevent future food shortages, as well as to produce preserved food for their upcoming sea voyage.

Tsukasa demands that Senku abandons science, but there’s no way he can do that. Tsukasa is left with no choice but to kill him.