Jean Pierre Polnareff holds the key to defeating the boss. The one who appeared before him wasn’t Bucciarati or his squad, but the leader of Passione, Diavolo himself. Diavolo tries to eliminate Polnareff once and for all and summons Emperor Crimson, but then Polnareff summons Silver Chariot and it is pierced with the arrow. That’s when something happens to everyone in or nearby the Colosseum. They find themselves losing strength and all fall asleep. After waking from their deep sleep, they all realize something has changed.

Bucciarati managed to win in his battle against Secco, but his body was reaching its limit. The boss had already arrived in Rome and used Doppio to get closer to Bucciarati. Bucciarati’s condition worsens and he mistakes Doppio as Trish and Doppio plays along. The man with the secret to defeating the boss was waiting for them inside the Colosseum. Time then skips and the boss’s true identity is revealed.

After a fierce battle, Giorno and Mista were able to strike down Cioccolata. However, Secco happens to receive one last voicemail from Cioccolata and finds out there’s a secret to defeating the boss at the Colosseum. Secco realizes that Cioccolata probably lost and heads to the Colosseum to find out what this secret is. Bucciarati attacks Secco in order to stop him from getting to the Colosseum, but Secco’s Sanctuary gives him trouble. An intense battle then takes place right in front of the Colosseum.

As soon as Ciccolata went up in a helicopter, Green Tea’s ability’s murderous range grew even more. He then flies to Rome and tries to spread his murderous mold. Bucciarati and the others go to stop Ciccolata, but Secco gets in their way. Giorno and Mista go after Ciccolata while Bucciarati faces off with Secco.

Bucciarati and the others end up facing off with 2 assassins sent by the boss, Cioccolata and Secco. Cioccolata uses his Stand Green Tea against them. His Stand creates a mold that makes living creatures rot away and he unleashed it upon the fishing village that Bucciarati and his crew arrived at. Bucciarati and the others manage to evade the attack for the most part and try to keep heading towards the Colosseum, but then Secco also uses his Stand, Sanctuary.

fter his death, Abbacchio was able to leave the others a copy of the boss’s face and fingerprints with Moody Jazz’s replay. The others try to find out who the boss is with the fingerprint and suddenly get contacted by someone. The mysterious man tells them that the boss’s name is Diavolo and tells them that the secret behind defeating him lies in the arrow. Bucciarati and the others head to Rome to meet him.

Doppio is on the brink of death after his fight with Risotto, but he manages to finish him off by having Narancia’s Li’l Bomber attack him. Bucciarati and Narancia go up onto the cliff to find the enemy that Li’l Bomber found and Abbacchio stays on the shore so he can use Moody Jazz to replay who exactly took the photo of Trish’s mother 15 years ago.

Risotto figures out that Doppio must be a Stand user that the boss trusts in deeply because he’s able to hear the noise from a certain Stand. Risotto then uses his Stand Metallic against him. Metallic is able to control magnetic force and attacks Doppio. Doppio uses the part of the boss’s power he received from him. While they’re fighting, Risotto realizes that Doppio’s personality and actions seem to be changing and he realizes exactly who Doppio is.

The summer of 1965... A woman gave birth to a baby boy inside a women’s prison that sat in the middle of the Adriatic Sea. Bizarrely, she hadn’t been near any man in two years, but somehow got pregnant now. Time passed, and a young man arrived at Sardinia. His name was Doppio. Meanwhile, the leader of the Hitman Team, Risotto, as well as Trish, Bucciarati and the rest of his team all arrive at Sardinia. Doppio encounters Risotto at Costa Smeralda.

The man who was killed by Mista at the airport, Carne, was first able to activate his stand, Notorious Chase, after he died. Notorious Chase reacts to movement and it attacks Giorno, resulting in him losing both arms. This makes him unable to use Golden Wind’s abilities, but he gives life to his brooch and recreates his left hand. Trish decides that she’s going to protect that left hand and goes after the brooch, but she’s detected. When all seemed lost, Trish’s Stand, Spicy Lady, was activated.

After defeating Squallo and Tiziano, Bucciarati and the others head off to Sardinia to find out about the boss's past. They head to Marco Polo International Airport in order to get a jet, but a strange man was following them. Mista manages to kill the strange Stand user before they're able to call upon their Stand. Even though they're a bit put off at how simple that was, they get onto the jet and fly off. But once they're on the jet, Giorno hears a weird noise...

The Stand that attacked Narancia was named Crush and belonged to Squallo, a member of the boss's elite guard. On top of that, Narancia suddenly can only say the exact opposite of what he's thinking, thanks to the ability of Talking Mouth, the Stand of Squallo's partner, Tiziano. Using Narancia, Squallo and Tiziano throw the team into chaos. The two elite guard members put Narancia in danger, but he boldly faces them so they can get out of Venice safely.

Because of their own wills and their sense of justice, Bucciarati and the others end up betraying the organization. Trish also wants to find out who her father truly is, so she tells the others that her mother met her father in Sardinia. They all decide to have a meal in Venice before they leave and Narancia is suddenly attacked by a Stand. The boss's own personal elite guard was now on the move.

Bucciarati finds out that the boss's true motive is to eliminate Trish because of her relationship with him, causing him to betray the boss and save Trish. Meanwhile, Giorno feels something bizarre is going on as they waited for Bucciarati's return. The boss's Stand, Emperor Crimson rises.

Mista and Giorno were able to defeat Ghiaccio. They then confirm the mission on the disc and head to the location they're supposed to take Trish. Bucciarati goes up the tower with Trish, but while they're in the elevator, Trish suddenly disappears. Bucciarati then realizes what the boss's true motives are.

Ghiaccio's Stand, White Ice is able to envelop him like a bodysuit and able to freeze everything around him to extremely low temperatures. Giorno and Mista somewhat make it to Venice, despite being partially frozen by Ghiaccio. But in order to try to get away from Ghiaccio, Giorno drives their car into the canal and they get stuck. Mista tries to sacrifice himself, but Giorno tells him that what's important right now isn't for him to sacrifice himself but for him to have resolve.

Using Babyhead's Stand's ability to turn human parts into other things, Giorno uses his Golden Wind to make parts for the human body. He rebuilds his own body and fights back. Meanwhile, another member of the Hitman Team who's also after Trish, Ghiaccio, was trying to regroup with Melone and was driving to Giorno's location.

After defeating Proscuitto and Pesci, Bucciarati and the others head to Venice in a car. Melone from the Hitman Team finds some of Bucciarati's blood at the scene where the train had stopped and then activates Babyhead. The powerful remote-control Stand created by assaulting a woman on the train then goes after Bucciarati.

Number Six from Six Bullets manages to warn Bucciarati about the enemies and fights back, but The Thankful Death's powers are taking a toll on him. Bucciarati steels his resolve and throws himself out with Proscuitto out of the train that's going 150kph. Barely hanging onto life, Proscuitto uses The Thankful Dead again. Pesci decides to take Proscuitto's resolve to heart and attacks Bucciarati.

In order to draw out Bucciarati and his crew, who are hiding somewhere on the train, Proscuitto uses his Stand The Thankful Dead's powers and turns everyone on the train old. Bucciarati and the others were hiding inside the turtle, but they also start to age. Mista goes out to try to fight back, but he's caught by Pesci's Stand, Fisher Man.