Tsuchimikado’s location spell backfires and leads Oriana straight to him, resulting an epic showdown. But he’s not the only one exposed to Oriana’s magic: Himegami feels the force of the spell caster’s power, and may not survive.

While Shirai frets about Misaka staying out again all night, she receives a visit from Kamijo, who manages to find Misaka's documents about the project. Kamijo catches up with Misaka on a bridge, where he tries to talk her out of doing anything rash.

Mikoto’s clones use their telepathic network to enlist Misaka 10032 to aid them in stopping Musujime from rebuilding the Tree Diagram in an effort to find out why humans are the only beings with esper powers.

Thwarted in her attempt to sabotage Tree Diagram, Misaka takes her frustration out on a nearby lab that is part of the project. Meanwhile, Accelerator and #10031 carry out their experiment, while Kamijo searches for Misaka's missing sister.

The battle over Orsola, the only nun who can read the Book of Law, continues as Toma is forced to act as an unwitting decoy. The Amakusa clash with church representatives, but the real culprit behind the plot might not be who Toma expected.

Misaka sets out on one last mission to put a halt to the experiments by destroying the supercomputer Tree Diagram. Meanwhile, Kamijo runs into Misaka's clone #10032 again, and the two of them decide what they should do about a stray kitten she has found.

Shirai, Konori, Kongo and friends, and Uiharu and Saten confront the powered suits at the four Assembly sites, where they soon receive backup. Misaka and Febrie move to take on Aritomi directly, but he has one final surprise up his sleeve for them.

Misaka and Kamijo meet again at the malfunctioning vending machine in the park, where Shirai mistakes him for being Misaka's boyfriend. Misaka becomes shaken when she bumps into another Misaka clone, and learns that the experiments are still ongoing.

Yuki must learn to like her new husband, Haruna can’t decide whether she wants to kiss - or kill - Ayumu, and the Necromancer disappears while no one is looking!

Having realized who Misaka is, Mugino decides to give her a run for her third-place ranking. When Frenda mistakenly leaves her doll-bombs behind while heading to the other facility, Misaka collects them and uses them to supplement her diminished powers.

When a talking Doberman shows up at the front door instead of the pizza man, Ayumu learns the tragic secret behind Eu’s powers. Oh yeah, there’s also a whale of a demon that needs to be put down!

As Misaka continues her way into the research facility, she and Mugino play a game of cat-and-mouse. Meanwhile, at the other facility, Nunotaba sneaks into a control room, planning to disrupt the experiment by adding a new factor to the Misaka Network.

As Nai and Gareki make their way towards the mysterious rainbow to see if Karoku is there, the rest of Circus work to wrap up what they can of the raid on the Kafka facility.

The members of the underworld organization ITEM finish one mission, and are called in to defend the remaining facilities. When Misaka tries to infiltrate one building, she encounters Item member Frenda. Meanwhile, Nunotaba drops in at the other facility.

Yogi going berserk sends the bad guys running, but when Nai senses that something is wrong with him, Tsukumo turns back alone, only to run into trouble herself.

Misaka manages to sabotage most of the experimental facilities remotely before she is cut off, leaving her to deal with the rest in person. Shirai resolves to help Misaka by doing her part to be more vigilant at work, but risks shutting the others out.